CMS OPPS proposal for 2027: deep cuts to 340B, ASC payment updates

CMS's proposed CY 2027 Outpatient Prospective Payment System (OPPS) and Ambulatory Surgical Center (ASC) rule includes significant policy shifts. The agency proposes to further cut payments for 340B drugs and advance site-neutral payment policies that would reduce reimbursement for hospital outpatient departments. For ASCs, the rule proposes a 2.5% payment update tied to a hospital market basket increase. Hospitals and ASCs should analyze the proposed impact tables, model the financial effect of the 340B and site-neutral changes, and prepare comments before the rule is finalized later this year.